Cobra 150 Tablets Price in Pakistan:
Cobra 150 tablets price in Pakistan is extremely famous among the gentlemen because of its very productive working. Cobra 150 tablets in Pakistan are utilized for the development of the extent of dick and it likewise working productively to increase the sexual stamina of the men. These are exceptionally acclaimed tablets because of its execution and something else about this tablet is it has no reaction on any piece of the human body. That is the reason people groups like and utilize it certainly because of its execution. Read more below about Cobra tablets in Urdu, timing wali tablet, cobra tablet price in Pakistan and black cobra 125 in Urdu.
Cobra Tablets in Urdu:
Cobra tablets in Pakistan are the tablets which are for the most part talked about subjects on web crawler these days because of its prominence. Cobra tablets in Urdu are likewise best for your sexual wellbeing and it additionally enhances your stamina with no symptom.
Timing Wali Tablet:
Timing Wali Tablet is the best to utilize and simple to get online from us. After the use of this tablets, you and your accomplice will extremely upbeat and make the most of their chance with each other wonderfully. When she feels the change in your penis estimate she will be stunned and exceptionally eager to get your penis on the bed. Furthermore, you likewise should appreciate the time because of increased sexual stamina it will be more charming time for you. Timing wali tablet which is cobra tablets will increase yourself certain which will be extremely useful in each field of your life. That is the reason individuals trust cobra tablets in Pakistan.
Cobra Tablet Price in Pakistan:
Cobra tablet price in Pakistan is exceptionally lower and less expensive than different tablets which rival our item. They will get a higher measure of cash from you and neglect to give you the best quality cobra tablet price in Pakistan. That is the reason in Pakistan cobra tablets are the very trusted from our clients and give positive surveys to us.
Black Cobra 125 in Urdu:
Black Cobra 125 in Urdu will get a proficient medicinal tablet for your wellbeing at the simple low price and have a larger number of professionals than others and one thing about black cobra 125 in Urdu is that these tablets have no symptom. We will convey these tablets on your doorstep which will be exceptionally appropriate and simple way to deal with get this tablet for you.
DRUG CLASS AND MECHANISM:
It has been estimated that impotence (erectile dysfunction, ED) affects 140 million men worldwide. Over half of all men with impotence are thought to have some physical (medical) cause. The remainder are believed to have psychogenic causes of impotence. Medical causes of impotence include diabetes and circulatory, neurological, or urological conditions.
Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase the delivery of blood and the blood vessels carrying blood away from the penis decrease the removal of blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis.
Sildenafil also reduces the pressure in the pulmonary artery in a serious condition called pulmonary arterial hypertension.
Sildenafil inhibits an enzyme called phosphodiesterase-5 (PDE5) which destroys the cGMP. Thus, sildenafil prevents the destruction of cGMP and allows cGMP to accumulate and persist longer. The longer cGMP persists, the more prolonged the engorgement of the penis.
PRESCRIPTION:
Yes
GENERIC AVAILABLE:
No
STORAGE:
Tablets should be kept at room temperature, 15- 30 C (59-86 F).
PRESCRIBED FOR:
Sildenafil is used for the treatment of erectile dysfunction of either organic (medical condition) or psychogenic (psychological) cause and for pulmonary arterial hypertension.
DOSING:
Sildenafil is rapidly absorbed. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state. When sildenafil is taken with a high fat meal, the rate of absorption is reduced, with an average delay in the time to maximal concentration of 1 hour.
DRUG INTERACTIONS:
Sildenafil increases the effects of the blood pressure lowering medications. It also increases the blood pressure lowering effects of nitrates, for example, isosorbide dinitrate (Isordil), isosorbide mononitrate (Imdur, Ismo, Monoket), nitroglycerin (Nitro-Dur, Transderm-Nitro) that are used primarily for treating angina. Patients taking nitrates should not receive sildenafil.
Patients should not combine sildenafil with Revatio (another form of sildenafil) or other PDE5 inhibitors (for example, vardenafil [Levitra], tadalafil [Cialis]).
Cimetidine (Tagamet), erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox) and mibefradil (Posicor) can cause marked increases in the amount of sildenafil in the body. Patients taking these medications should be observed carefully if sildenafil is used.
It is expected that rifampin will decrease blood levels of sildenafil and probably reduce its effectiveness.
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